Obtain serum digoxin levels in patients with signs or symptoms of digoxin therapy and interrupt or adjust dose if necessary see adverse reactions 6 and overdosage 10 .

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These are important findings in terms of trying to quantify the size of the increased riskHoweverthere are points to consider:

Overallthe review found that people taking digoxin had a 21higher risk of death from any cause compared to people not taking the drug.

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continue monitoring during concomitant treatment and increase the digoxin dose by 20 to 40 as necessary.

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