A lisinopril prinivil, zestril is approved for use alone or in combination with other medications to treat hypertension high blood pressure .
If you forget to take a dosetake it as soon as you rememberHoweverif it is nearly time for the next doseskip the missed doseDo not take a double dose to make up for a forgotten dose.
Preclinical data reveal no special hazard for humans based on conventional studies of general pharmacologyrepeated dose toxicitygenotoxicityand carcinogenic potentialAngiotensin-converting enzyme inhibitorsas a classhave been shown to induce adverse effects on the late foetal developmentresulting in foetal death and congenital effectsin particular affecting the skullFoetotoxicityintrauterine growth retardation and patent ductus arteriosus have also been reportedThese developmental anomalies are thought to be partly due to a direct action of ACE inhibitors on the foetal renin-angiotensin system and partly due to ischaemia resulting from maternal hypotension and decreases in foetal-placental blood flow and oxygen/nutrients delivery to the foetus.
Your blood pressure will need to be checked oftenand you may need frequent blood tests.
Zestril is also used to treat congestive heart failure in adultsor to improve survival after a heart attack.
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in a study in 36 patients with mild to moderate hypertension where the antihypertensive effects of zestril alone were compared to zestril given concomitantly with indomethacin, the use of indomethacin was associated with a reduced effect, although the difference between the two regimens was not significant.