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Otherless than 2Anaphylaxisbronchospasmtachycardiaanginahypokalemiaelectrocardiographic alterationsvascular occlusive eventsand grand mal seizuresExcept for bronchospasm and anaphylaxisthe relationship to ZOFRAN is unclear.

There is no specific antidote for ondansetron overdosePatients should be managed with appropriate supportive therapy.

Zofran and other 5-GT3 receptor antagonists are considered antiemetic agentsThese are any drugs that prevent vomiting or nausea including over-the-counter antihistaminesBenadrylDramamineor bismuth subsalicylatePepto-BismolKaopectate

Table 1Adult Recommended Dosage Regimen for Prevention of Nausea and Vomiting.

The FDA had previously noted that ondansetron could increase the risk of developing QT interval prolongationThe agency also pointed to vistaril buy. articles published in the medical literature that describe QT interval prolongation with ondansetron.

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