Fasn inhibition with orlistat in scc-9 cells was verified by incorporation studies of 14 c-acetate, which demonstrated a significant reduction of the total lipid production fig.
Table 4 illustrates the percentage of adult patients on XENICAL and placebo who developed a low vitamin level on two or more consecutive visits during 1 and 2 years of therapy in studies in which patients were not previously receiving vitamin supplementation.
Orlistat is used to aid in weight lossor to help reduce the risk of regaining weight already lostThis medicine must be used together with a reduced-calorie dietOrlistat is for use only in adults.
Patients should be informed of potential risks which include lowered absorption of fat-soluble vitamins and potential liver injuryincreases in urinary oxalateand cholelithiasissee WARNINGS AND PRECAUTIONSTreatment with XENICAL may result in weight loss and improvement in obesity-related risk factors due to weight losssee Clinical Studies
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alli orlistat 60 mg is the only otc drug for weight loss that is fda approved.