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Efficacy was assessed with the Daily Record of Severity of ProblemsDRSPa patient-rated instrument that mirrors the diagnostic criteria for PMDD as identified in the DSM-IVand includes assessments for moodphysical symptomsand other symptomsOther efficacy assessments included the Hamilton Rating Scale for DepressionHAMD-17and the Clinical Global Impression Severity of IllnessCGI-Sand ImprovementCGI-Iscores.
Your family or other caregivers should also be alert to changes in your mood or symptomsYour doctor will need to check you at regular visits for at least the first 12 weeks of treatment.
Nausealoss of appetitediarrheaand indigestion change in sleep habitsincluding increased sleepiness and insomnia increased sweating sexual problemsincluding decreased sex drive and ejaculation failure tremor or shaking tiredness and fatigue agitation.
Takingor within 14 days of stoppingMAOIsincluding the MAOIs linezolid and intravenous methylene bluebecause of an increased risk of serotonin syndromeSee WARNINGS AND PRECAUTIONSDRUG INTERACTIONSTaking pimozideSee DRUG INTERACTIONSWith known hypersensitivity to sertralinee.ganaphylaxisangioedemaSee ADVERSE REACTIONS
This drug is used to treat major depressive disorderobsessive-compulsive disorderpanic disorderposttraumatic stress disordersocial anxiety disorderand premenstrual dysphoric disorder.
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patients taking zoloft should be closely monitored by family and caregivers especially during the first couple month of the course.