To generate sgcd tg mice, sgcd females were mated with serpina3n tg males and siblings from these litters were subsequently mated, and the third generation was analyzed.
Other SERPINA1 gene mutations lead to the production of an abnormally small form of alpha-1 antitrypsin that is quickly broken down in the liverAs a resultlittle or no alpha-1 antitrypsin is available in the lungsWhile the liver remains healthy in individuals with these mutationsthe lungs are left unprotected from neutrophil elastase.
This section is used to point to information related to entries and found in data collections other than UniProtKB.
It should be noted that whilein theorytwo different sequences could have the same checksum valuethe likelihood that this would happen is extremely low.
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