No information is available from controlled clinical studies regarding the use of voltaren in patients with advanced renal disease.
Digestive Systemcolitiseructationfulminant hepatitis with and without jaundiceliver failureliver necrosispancreatitis.
In postmarketing reportscases of drug-induced hepatotoxicity have been reported in the first monthand in some casesthe first 2 months of therapybut can occur at any time during treatment with diclofenacPostmarketing surveillance has reported cases of severe hepatic reactionsincluding liver necrosisjaundicefulminant hepatitis with and without jaundiceand liver failureSome of these reported cases resulted in fatalities or liver transplantation.
Elderly patients should take the minimum number of tablets or suppositories that provides relief of symptomsElderly patientsespecially those with a low body weightmay be more sensitive to the effects of Voltaren than other adults.
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